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Throughout these guidelines, quality laboratory science is reinforced by a common-sense approach to biosafety in day-to-day activities.Because many of the same diagnostic techniques are used in human and animal diagnostic laboratories, the text is presented with this in mind.

Work in a diagnostic laboratory entails safety considerations beyond the biological component; therefore, these guidelines also address a few of the more important day-to-day safety issues that affect laboratorians in settings where biological safety is a major focus. An estimated 500,000 persons in all professions work in human and animal diagnostic laboratories.In addition, some members of the panel were representatives of the biosafety community.The Blue Ribbon Panel recommended that biosafety guidelines be developed to address the unique operational needs of the diagnostic laboratory community and that they be science based and made available broadly.Needle puncture, glass cuts, splash in eye, and bruises and cuts have the highest potential for infection from microbes.

In the hematology laboratory, the major causes of injuries are likely to be exposure to blood and body fluids; needle sticks, aerosols from centrifuge or removal of tube stoppers, tube breakage; or contaminated gloves (22).

Any of these workers who have chronic medical conditions or receive immunosuppressive therapy would be at increased risk for a laboratory-acquired infection (LAI) after a laboratory exposure.